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Vasopressin, ADH injection What is vasopressin injection? VASOPRESSIN (antidiuretic hormone [ADH] ) is a hormone that is normally produced by the pituitarygland. Vasopressin helps to keep a regular balance of salts in the blood and tocontrol the amount and frequency of urination. Without vasopressin too muchwater is lost in the urine. Vasopressin helps to prevent or control frequenturination, excessive thirst, and dehydration associated with diabetes insipidus. Vasopressin cannot be given by mouth because itis destroyed in the stomach. Generic vasopressin injections are available. What should I tell my health careprovider before I take this medicine? They need to know if you have any of these conditions: •asthma •blood vessel disease •goiter •heart disease •high blood pressure •kidney disease •migraine •seizures (convulsions) •an unusual or allergic reaction to vasopressin, other medicines, foods,dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should I use this medicine? Vasopressin is for injection into a muscle, or under the skin. If you have beeninstructed to give yourself vasopressin injections, make sure that youunderstand how to prepare and inject the dose. Use exactly as directed. Do notexceed the prescribed dose, and do not use more or less often than prescribed.In some cases vasopressin may be injected into a vein by means of a slowinfusion pump. This keeps a steady flow of vasopressin into the body.
Contact your pediatrician or health care professional regarding the use of thismedicine in children. Special care may be needed. What if I miss a dose? If you use two or more doses per day, use the missed dose as soon as youremember. If it is nearly time for the next dose, skip the missed dose andresume your regular schedule with the next dose. Do not use double doses.
If you use one dose per day, use the missed dose as soon as you remember on theday the dose was due. If you do not remember until the next day, skip themissed dose and resume your regular schedule with the next dose. Do not usedouble doses. What drug(s) may interact withvasopressin? •alcohol •carbamazepine •chlorpropamide •clofibrate •cyclophosphamide •demeclocycline •epinephrine •fludrocortisone •heparin •medicines for mental depression •morphine
Tell your prescriber or health care professional: about all other medicines youare taking including non-prescription medicines; if you are a frequent user ofdrinks with caffeine or alcohol; if you smoke; or if you use illegal drugs.These can affect the way your medicine works. Check with your health careprofessional before stopping or starting any of your medicines. What side effects might I noticefrom receiving vasopressin? Side effects that you should report to your prescriber or health careprofessional as soon as possible: •chest pain •confusion •difficulty breathing, wheezing •difficulty passing urine •drowsiness •listlessness •pain, redness, irritation, or swelling at the injection site •rapid weight gain •seizures (convulsions) •severe or continuing headaches •skin rash, itching (hives)
Side effects that usually do not require medical attention (report to yourprescriber or health care professional if they continue or are bothersome): •belching, stomach gas •dizziness or fainting •flushing, reddening of the skin •headaches •nausea, vomiting •pale area around the mouth •stomach pain or cramps •sweating •trembling •uterine cramps, or vaginal pain What should I watch for whiletaking vasopressin? Visit your prescriber or health care professional for regular checks on yourprogress.
Drinking 1 or 2 glasses of water when the hormone is injected may prevent orreduce some side effects. However, vasopressin prevents the loss of water. Toomuch water in the body dilutes normal body fluids and can cause confusion,drowsiness, or lethargy, which may lead to seizures or coma. The risk of toomuch water in the body is greater in young children and the elderly. Ask yourprescriber or health care professional for advice about your fluid intake. Where can I keep my medicine? Keep out of the reach of children.
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