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Insulin Aspart; Insulin Aspart Protamine injection Insulin Aspart;Insulin Aspart Protamineinjection What is Insulin Aspart; Insulin Aspart Protamine injection?
INSULIN ASPART; INSULIN ASPART PROTAMINE (NovoLog®Mix)is a human-made form of insulin. Insulin is a hormone produced naturally by thepancreas. Insulin lowers the amount of sugar in your blood. Keeping your bloodsugar close to normal prevents or reduces long-term complications of diabetesincluding damage to the blood vessels, eyes, kidneys, or nerves. Insulin aspart; insulin aspart protamine is a mixture of a rapid-acting insulin and alonger-acting insulin. Insulin aspart; insulin aspart protamine starts working10—20 minutes after injection and continues to work for as long as12—24 hours. Because of the quick onset of action, you should eat a mealwithin 5—10 minutes after injecting your dose of insulin aspart; insulin aspart protamine. This will help reduce the risk of low bloodsugar (hypoglycemia). The time-course of action of insulin may vary indifferent people and at different times in the same person. The time-course ofaction of insulin may also vary depending on the place where the insulin isinjected, your body temperature, and your physical activity. A prescriptionfrom you health care prescriber is needed to buy insulin aspart;insulin aspart protamine. Aprescription to obtain insulin syringes may or may not be required in the statewhere you live.
There are different types of insulin available. Each type has a different onsetof action and a different duration of action in the body. You should learnwhich types you take and how you should administer them, and how each type actsin your body. Insulin aspart; insulin aspart protamine is labeled withits name, NovoLog®Mix 70/30. Insulin is obtainedfrom beef, pork, or human sources.Beef insulin is nolonger made in the USbecause of concerns of cow tissues spreading certain infections.
Do not change the type of insulin you take without talking to your prescriber.If you must switch the type of insulin you use, you should realize that you mayneed to monitor your blood sugar more frequently and that dosage adjustmentsmay be needed before you are stabilized on the new type. Take care to learn andrecognize the symptoms of hypoglycemia (low blood sugar) and know how youshould treat these reactions. What should I tell my healthcare provider before I take this medicine?
They need to know if you have any of these conditions:
•adrenal or pituitary gland problems
•diarrhea
•fever or infection
•injury or trauma
•kidney disease
•liver disease
•nausea, vomiting
•recent surgery
•thyroid disease
•pregnant or trying to get pregnant
•breast-feeding
•an unusual or allergic reaction to insulin, metacresol,other medicines, foods, dyes, or preservatives How should this medicine beused?
Insulin is for injection under the skin. Use exactly as directed. Do not usemore insulin than prescribed. Do not use more or less often than prescribed. Itis important to follow the directions given to you by your health careprofessional or prescriber. You will be taught how to inject insulin. If youutilize an insulin injector device, you will be taught how to use it and how torefill the device with the insulin cartridges.
Your health care professional or prescriber or will tell you how long to waitafter you inject your dose of insulin aspart; insulinaspart protamine beforeeating a meal. Most of the time, you should wait about 5—10 minutes orless. You will also be taught how to adjust doses for activities and illness.
Always check the appearance of your insulin before using it. Insulin aspart; insulin aspart protamine should be white and cloudy. Do not use insulin aspart; insulin aspart protamine if it is not uniformly cloudy after mixing. Tomix insulin aspart; insulin aspartprotamine, roll the vial gently 10 times in yourhands. If using a cartridge that is to be inserted into an insulin deliverydevice (for example a pen), before inserting into the delivery device, roll thecartridge gently 10 times in your hands. After insertion into the deliverydevice, turn the device upside down so that the glass ball moves one end of thecartridge to the other. Do this at least 10 times. Make sure to perform themixing procedures before each injection.
Do not mix insulin aspart; insulin aspart protamine with any otherinsulin or diluent. What if I miss a dose?
It is important not to miss a dose. Your health care professional orprescriber should discuss a plan for missed doses with you. If you do miss adose, follow their plan. Do not take double doses. Know the signs of low andhigh blood sugar and make sure a close family member or friend can alsorecognize these signs. Contact your health care professional or prescriber atonce if you have any problems. What drug(s) may interact withInsulin Aspart; Insulin AspartProtamine?
•other medicines for diabetes
Many medications may cause changes (increase or decrease) in blood sugar, theseinclude:
•alcohol containing beverages
•angiotensin converting enzyme inhibitors (ACEinhibitors), often used for high blood pressure or heart problems (examplesinclude captopril, enalapril,lisinopril)
•antiretroviral protease inhibitors (examples include indinavir,ritonavir, saquinavir)
•aspirin and aspirin-like drugs
•beta-blockers, often used for high blood pressure or heart problems(examples include atenolol, metoprolol,propranolol)
•certain medicines used for mental depression, emotional, or psychoticdisturbances
•chromium
•cisapride
•clonidine
•cyclosporine
•danazol
•diazoxide
•disopyramide
•epinephrine
•female hormones, such as estrogens, progestins,or contraceptive pills
•fenofibrate
•gemfibrozil
•glucagon
•growth hormone (somatropin)
•guanethidine
•isoniazid
•lithium
•metoclopramide
•male hormones or anabolic steroids
•medications to suppress appetite or for weight loss
•medicines for allergies, asthma, cold, or cough
•niacin
•nicotine (including nicotine found in patches and gum)
•pentamidine
•pentoxifylline
•phenytoin
•propoxyphene
•quinolone antibiotics, medicines used forinfections (examples include ciprofloxacin, levofloxacin,norfloxacin)
•some herbal dietary supplements
•steroid medicines such as prednisone or cortisone
•sulfonamides, medicines for infection ( examples include Azulfidine®, Bactrim®, Gantrisin® Septra®)
•tacrolimus
•thyroid hormones
•water pills (diuretics)
Some medications can hide the warning symptoms of low blood sugar(hypoglycemia). You may need to monitor your blood sugar more closely if youare taking one of these medications. These include:
•beta-blockers, often used for high blood pressure or heart problems(examples include atenolol, metoprolol,propranolol)
•clonidine
•guanethidine
•reserpine
Tell your prescriber or health care professional about all other medicines youare taking, including non-prescription medicines, nutritional supplements, orherbal products. Also tell your prescriber or health care professional if youare a frequent user of drinks with caffeine or alcohol, if you smoke, or if youuse illegal drugs. These may affect the way your medicine works. Check withyour health care professional before stopping or starting any of yourmedicines. What side effects may I noticefrom receiving Insulin Aspart; Insulin Aspart Protamine?
Learn how and when you should monitor your blood sugar, and what you should doif high or low blood sugar occurs. Side effects that you should report to yourhealth care professional or prescriber as soon as possible:
Symptoms of hypoglycemia (low blood glucose):
•anxiety or nervousness, confusion, difficulty concentrating, hunger,pale skin, nausea, fatigue, sweating, headache, palpitations, numbness of themouth, tingling in the fingers, tremors, muscle weakness, blurred vision, coldsensations, uncontrolled yawning, irritability, rapid heartbeat, shallowbreathing, and loss of consciousness. You should learn to recognize your ownsymptoms of hypoglycemia. Your symptoms may be different than others. If youare uncertain about your symptoms of hypoglycemia, check your blood sugar oftento help you learn to recognize the symptoms. Hypoglycemia may cause you to notbe aware of your actions or surroundings if it is severe, so you should letothers know what to do if you cannot help yourself in a severe reaction. Yourhealth care professional or prescriber will teach you how to treathypoglycemia. Always carry a quick source of sugar such as candies or glucosetablets with you.
Symptoms of high blood sugar (hyperglycemia):
•dizziness, dry mouth, flushed dry-skin, fruit-like breath odor, loss ofappetite, nausea, stomach ache, unusual thirst, frequent passing of urine
Insulin also can cause rare but serious allergic reactions in some patients,including:
•severe skin rash and itching (hives)
•difficulty breathing
Side effects that usually do not require medical attention (report to yourhealth care professional or prescriber if they continue or are bothersome):
•increase or decrease in fatty tissue under the skin, through overuse ofa particular injection site
•itching, burning, swelling, or rash at the injection site What should I watch for whiletaking Insulin Aspart; Insulin AspartProtamine?
Visit your health care professional or prescriber for regular checks onyour progress. To control your diabetes properly you must use insulin regularlyand follow a regular diet and exercise schedule. Diabetes cannot be cured.Careful, daily control of blood sugar can postpone or prevent many of thelong-term complications of diabetes.
Dangerously high or low blood sugar can occur when meals and insulin are notspaced properly. Checking and recording your blood glucose and urine ketone levels regularly is important. Sometimes it is hardto tell the difference between low and high blood sugar (see side effects). Usea glucometer (blood glucose or sugar measuringdevice), whenever possible, before you treat high or low blood sugar.
Always carry a quick-source of sugar with you in case you have symptoms of lowblood sugar (hypoglycemia). Examples include hard sugar candy or glucosetablets.
Make sure that you have the right kind of syringe for the type of insulin youuse. Try not to change the brand and type of insulin syringe unless your healthcare professional or prescriber tells you to. Use a syringe one time only. Throwaway syringe and needle in a closed container to prevent accidental needlesticks.
Do not switch brands or types of insulin without consulting your health careprofessional or prescriber. Switching insulin brand or type can causedangerously high or low blood sugar.
Always keep an extra supply of insulin, syringes, and needles on hand.
Wear a Medic Alert bracelet or necklace and/or carry an identification cardwith your name and address, condition, medication, and prescriber"sname and address.
If you develop a cold, diarrhea, vomiting, or other infection or illness, youshould contact your health care professional or prescriber. "Sick-days" mayrequire changes to your insulin dosage. Or your illness may need to beevaluated. Ask your health care professional or prescriber what you should doif you become ill. Do not stop taking your insulin; check with your health careprofessional or prescriber for advice.
If you are a long time smoker and suddenly stop, you may need a change ininsulin dose. Talk to your health care professional or prescriber first.
Many nonprescription cough and cold products contain sugar or alcohol. Thesecan affect diabetes control or can alter the results of tests used to monitorblood sugar. Avoid alcohol. Avoid products that contain alcohol or sugar.
If you are going to have surgery, make sure you tell the health careprofessionals that you take insulin. Where can I keep my medicine?
Keep out of the reach of children.
Store unopened insulin vials in a refrigerator between 2—8 degrees C(36—46 degrees F). Do not freeze or use if the insulin has been frozen.Opened vials (vials currently in use) may be stored in the refrigerator or atroom temperature, at approximately 30 degrees C (86 degrees F) or cooler. Keepingyour insulin at room temperature decreases the amount of pain during injection.Once opened, your insulin can be used for 28 days. After 28 days, the vial ofinsulin should be thrown away.
Store unopened cartridges or FlexPen® in arefrigerator between 2—8 degrees C (36—46 degrees F.) Do not freezeor use if the insulin has been frozen. Once opened, the FlexPen®or cartridges that are inserted into pens should be kept at room temperature,approximately 25 degrees C (77 degrees F) or cooler. Do not store in the refrigerator.Once opened, the insulin can be used for 14 days. After 14 days, the cartridgeor FlexPen® should be thrown away.
Protect from light and excessive heat. Throw away any unused medicine after theexpiration date or after the specified time for room temperature storage haspassed.
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