What is Humira (adalimumab) ?
HUMIRA (adalimumab),a new product produced by recombinant DNA technology, has been approved by theFDA to treat rheumatoid arthritis.
HUMIRA is a human-derivedantibody that binds to human tumor necrosis factor alpha (TNF alpha). TNF isnaturally produced by the body and is involved with normal inflammatory andimmune responses.
People with rheumatoid arthritis,a disease that affects more than 2 million Americans, have high levels of TNFin the lubricating fluid in joints (synovial fluid).The extra TNF plays an important role in both the pathologic inflammation andthe joint destruction that are hallmarks of rheumatoid arthritis. By workingagainst the inflammatory process, HUMIRA, like other TNF blockers, has provedto be effective in controlling symptoms of the disease.
HUMIRA is indicated for reducingsigns and symptoms and inhibiting the progression of structural damage in adultpatients with moderately to severely active rheumatoid arthritis who have hadan inadequate response to one or more disease-modifying anti-rheumatic drugs.
This is a summary of the mostimportant information about Humira. For details, talk to your healthcare professional.
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