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Glucophage (Metformin HCl )
Glucophage  (Metformin HCl )
Item #: PD000394
Category: Prescription Drugs
Price: $66.99
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PrescriptionGaint
500mg Tablets   $66.99
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1000mg Generic Tablets   $3.99
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What are metformin tablet and metforminextended-release tablet?

Metformintablet and metformin extended-release tablet are used to treat type 2 diabetes. This is also known as non-insulin-dependentdiabetes mellitus. People with type 2 diabetes are not able to make enoughinsulin or respond normally to the insulin their bodies make. When this happens, sugar (glucose)builds up in the blood. This can lead to serious medical problems includingkidney damage, amputations, and blindness. Diabetes is also closely linked toheart disease. The main goal of treating diabetes is to lower your blood sugarto a normal level.

High bloodsugar can be lowered by diet and exercise, by a number of medicines taken bymouth, and by insulin shots. Before you take metformin tablet or metforminextended-release tablet, try to control your diabetes by exercise and weightloss. While you take your diabetes medicine, continue to exercise and followthe diet advised for your diabetes. No matter what your recommended diabetesmanagement plan is, studies have shown that maintaining good blood sugarcontrol can prevent or delay complications of diabetes, such as blindness.

Metformintablet and metformin extended-release tablet have the same active ingredient.However, metformin extended-release tablet works longer in your body. Both ofthese medicines help control your blood sugar in a number of ways. Theseinclude helping your body respond better to the insulin it makes naturally,decreasing the amount of sugar your liver makes, and decreasing the amount ofsugar your intestines absorb. metformin tablet and metformin extended-releasetablet do not cause your body to make more insulin. Because of this, when takenalone, they rarely cause hypoglycemia (low blood sugar), and usually do notcause weight gain. However, when they are taken with a sulfonylurea or withinsulin, hypoglycemia is more likely to occur, as is weight gain.

WARNING: Asmall number of people who have taken metformin tablet have developed a seriouscondition called lactic acidosis. Lactic acidosis is caused by a buildup oflactic acid in the blood. This happens more often in people with kidneyproblems. Most people with kidney problems should not take metformin tablet or metforminextended-release tablet. (See “What are the side effects of metformin tabletand metformin extended-release tablet?”)

Who should not take metformin tabletor metformin extended-release tablet?

Someconditions increase your chance of getting lactic acidosis, or cause otherproblems if you take either of these medicines. Most of the conditions listedbelow can increase your chance of getting lactic acidosis.

Do not takemetformin tablet or metformin extended-release tablet if you:

  • have kidney problems
  • have liver problems
  • have heart failure that is treated with medicines, such as LanoxinÒ (digoxin) or LasixÒ (furosemide)
  • drink a lot of alcohol. This means you binge drink for short periods or drink all the time
  • are seriously dehydrated (have lost a lot of water from your body)
  • are going to have an x-ray procedure with injection of dyes (contrast agents)
  • are going to have surgery
  • develop a serious condition, such as heart attack, severe infection, or a stroke
  • are 80 years or older and you have NOT had your kidney function tested

Tell yourdoctor if you are pregnant or plan to become pregnant. metformin tablet and metforminextended-release tablet may not be right for you. Talk with your doctor aboutyour choices. You should also discuss your choices with your doctor if you arenursing a child.

Can metformin tablet or metforminextended-release tablet be used in children?

Metformintablet has been shown to effectively lower glucose levels in children (ages 10to 16 years) with type 2 diabetes. metformintablet has not been studied in children younger than 10 years old. metformin tablet has not been studied incombination with other oral glucose-control medicines or insulin inchildren. If you have any questionsabout the use of metformin tablet in children, talk with your doctor or otherhealthcare provider.

Metformin extended-release tablethas not been studied in children.

How should I take metformin tabletor metformin extended-release tablet?

Your doctorwill tell you how much medicine to take and when to take it. You will probablystart out with a low dose of the medicine. Your doctor may slowly increase yourdose until your blood sugar is better controlled. You should take metformintablet or metformin extended-release tablet with meals.

Your doctormay have you take other medicines along with metformin tablet or metforminextended-release tablet to control your blood sugar. These medicines mayinclude insulin shots. Taking metformin tablet or metformin extended-releasetablet with insulin may help you better control your blood sugar while reducingthe insulin dose .

Continueyour exercise and diet program and test your blood sugar regularly while takingmetformin tablet or metformin extended-release tablet. Your doctor will monitor your diabetesand may perform blood tests on you from time to time to make sure your kidneysand your liver are functioning normally. There is no evidence that metformintablet or metformin extended-release tablet causes harm to the liver orkidneys.

Tell yourdoctor if you

  • have an illness that causes severe vomiting, diarrhea or fever, or if you drink a much lower amount of liquid than normal. These conditions can lead to severe dehydration (loss of water in your body). You may need to stop taking metformin tablet or metformin extended-release tablet for a short time.
  • plan to have surgery or an x-ray procedure with injection of dye (contrast agent). You may need to stop taking metformin tablet or metformin extended-release tablet for a short time.
  • start to take other medicines or change how you take a medicine. metformin tablet and metformin extended-release tablet can affect how well other drugs work, and some drugs can affect how well metformin tablet and metformin extended-release tablet work. Some medicines may cause high blood sugar.

What should I avoid while taking metformintablet or metformin extended-release tablet?

Do notdrink a lot of alcoholic drinks while taking metformin tablet or metforminextended-release tablet. This means you should not binge drink for shortperiods, and you should not drink a lot of alcohol on a regular basis. Alcoholcan increase the chance of getting lactic acidosis.

What are the side effects of metformintablet and metformin extended-release tablet?

Lactic Acidosis. In rare cases, metformin tablet andmetformin extended-release tablet can cause a serious side effect called lacticacidosis. This is caused by a buildup of lactic acid in your blood. This build-up can cause serious damage.Lactic acidosis caused by metformin tablet and metformin extended-releasetablet is rare and has occurred mostly in people whose kidneys were not workingnormally. Lactic acidosis has been reported in about one in 33,000 patientstaking metformin tablet over the course of a year. Although rare, if lactic acidosis doesoccur, it can be fatal in up to half the people who develop it.

It is alsoimportant for your liver to be working normally when you take metformin tabletor metformin extended-release tablet. Your liver helps remove lactic acid fromyour blood.

Make sureyou tell your doctor before you use metformin tablet or metforminextended-release tablet if you have kidney or liver problems. You should also stopusing metformin tablet or metformin extended-release tablet and call yourdoctor right away if you have signs of lactic acidosis. Lactic acidosis is amedical emergency that must be treated in a hospital.

Signs of lactic acidosis are:

  • feeling very weak, tired, or uncomfortable
  • unusual muscle pain
  • trouble breathing
  • unusual or unexpected stomach discomfort
  • feeling cold
  • feeling dizzy or lightheaded
  • suddenly developing a slow or irregular heartbeat

If yourmedical condition suddenly changes, stop taking metformin tablet or metforminextended-release tablet and call your doctor right away. This may be a sign oflactic acidosis or another serious side effect.

Other Side Effects. Common side effects of metformin tablet and metforminextended-release tablet include diarrhea, nausea, and upset stomach. These sideeffects generally go away after you take the medicine for a while. Taking yourmedicine with meals can help reduce these side effects. Tell your doctor if theside effects bother you a lot, last for more than a few weeks, come back afterthey’ve gone away, or start later in therapy. You may need a lower doseor need to stop taking the medicine for a short period or for good.

About 3 outof every 100 people who take metformin tablet or metformin extended-releasetablet have an unpleasant metallic taste when they start taking the medicine.It lasts for a short time.

Metformintablet and metformin extended-release tablet rarely cause hypoglycemia (lowblood sugar) by themselves. However, hypoglycemia can happen if you do not eatenough, if you drink alcohol, or if you take other medicines to lower bloodsugar.

General advice about prescriptionmedicines

If you havequestions or problems, talk with your doctor or other healthcare provider. Youcan ask your doctor or pharmacist for the information about metformin tabletand metformin extended-release tablet that is written for health careprofessionals. Medicines are sometimes prescribed for purposes other than thoselisted in a patient information leaflet. Do not use metformin tablet or metforminextended-release tablet for a condition for which it was not prescribed. Do notshare your medicine with other people.

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