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Details:
Mechanism of Action:
The mechanism of action of dapsone gel in treating acne vulgaris is not known.
INDICATIONS AND USAGE
ACZONE Gel 5% is indicated for the topical treatment of acne vulgaris.
Glucose 6-phosphate dehydrogenase (G6PD) levels should be obtained prior to initiating therapy with ACZONE Gel 5%.
In patients with a history of anemia and predisposition to increased hemolytic effect with dapsone (e.g., glucose-6-phosphate
dehydrogenase deficiency), closer follow-up for blood hemoglobin levels and reticulocyte counts should be implemented.
Alternatively, other therapies for acne than ACZONE Gel 5% may be considered.
CONTRAINDICATIONS
ACZONE Gel 5% is contraindicated in persons with a hypersensitivity to dapsone or any other component of the formulation
What should I tell my doctor before using ACZONE Gel?
Tell your doctor about all of your medical conditions, including if you:
• are pregnant or planning to become pregnant.
It is not known if ACZONE Gel may harm your unborn baby.
• are breastfeeding. ACZONE Gel passes into your milk and may harm your baby.
You should choose either to use ACZONE Gel, or breastfeed, but not both. Talk to you doctor about the best way to feed your baby while using ACZONE Gel.
• have a history of anemia or have been diagnosed with glucose-6-phosphate dehydrogenase deficiency
Tell your doctor about all the medicines you are taking including prescription and nonprescription medicines,
vitamins and herbal supplements. Especially, tell your doctor if you are using any other medicines applied to the skin.
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